Human PBMC atlas - T/NK proliferating cells

Prolif T CD8 CTL mito

Full Name: proliferating mito CD8-positive, alpha-beta cytotoxic T cell
Closest Ontology Term: CD8-positive, alpha-beta cytotoxic T cellCL:0000794
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: CD8-positive, alpha-beta cytotoxic T cellCL:0000794
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster expresses canonical cytotoxic CD8 T cell markers and mitochondiral genes in addition to markers of proliferation
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MT-ATP8
Canonical Marker Genes: CD8, GNLY, MKI67, TOP2A, STMN1
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: Cluster expresses canonical cytotoxic CD8 T cell markers and mitochondiral genes in addition to markers of proliferation
Rationale DOI: https://doi.org/10.18632/aging.203113

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual