Human PBMC atlas - T/NK proliferating cells

Prolif T CD8 EM - Proli 2

Full Name: proliferating 2 effector memory CD8-positive, alpha-beta T cell
Closest Ontology Term: effector memory CD8-positive, alpha-beta T cellCL:0000913
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: effector memory CD8-positive, alpha-beta T cellCL:0000913
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster expresses canonical effector CD8 T cell markers in addition to markers of proliferation. Similar clusters are numbered by degree of proliferation 1-3.
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: unknown
Canonical Marker Genes: CD8, GZMK, MKI67, TOP2A, STMN1
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: Cluster expresses canonical effector CD8 T cell markers in addition to markers of proliferation. Similar clusters are numbered by degree of proliferation 1-3.
Rationale DOI: https://doi.org/10.18632/aging.203113

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual