Human PBMC atlas - HSCs

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Cell Metadata

HSC_MPP_CD38lo (HSC-like)

Full Name: quiescent CD34-positive, CD38-negative hematopoietic stem cell
Closest Ontology Term: CD34-positive, CD38-negative hematopoietic stem cellCL:0001024
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: hematopoietic stem cellCL:0000037
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster with canonical HSC markers but CD38 low and ribosomal genes suggesting quiescence
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: AVP, RPS10
Canonical Marker Genes: CD34
Rationale: Cluster with canonical HSC markers but CD38 low and ribosomal genes suggesting quiescence
Rationale DOI: https://doi.org/10.1038/bcj.2011.35

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual

Full Name: quiescent CD34-positive, CD38-negative hematopoietic stem cell
Closest Ontology Term: CD34-positive, CD38-negative hematopoietic stem cellCL:0001024
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: hematopoietic stem cellCL:0000037
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster with canonical HSC markers but CD38 low and ribosomal genes suggesting quiescence
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: AVP, RPS10
Canonical Marker Genes: CD34
Rationale: Cluster with canonical HSC markers but CD38 low and ribosomal genes suggesting quiescence
Rationale DOI: https://doi.org/10.1038/bcj.2011.35

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual