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Human PBMC atlas - HSCs | CAP
v5
Single cell atlas of the human peripheral immune system
Human PBMC atlas - HSCs
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Cell Metadata
Level_4
Level_1
Level_2
Level_3
Human PBMC atlas - HSCs
Summary
Our HSC dataset includes 11,247 cells, using canonical markers to distinguish 7 unique subsets.
Metadata
Dataset Type
Integrated. The file includes an integrated collection of datasets.
Total Cells
11,192
organism
Homo sapiens
tissue
blood
assay
10x 5' v1
(7,706 cells)
10x 3' v2
(2,120 cells)
10x 3' v3
(1,211 cells)
10x 5' v2
(155 cells)
disease
COVID-19
(5,953 cells)
normal
(3,646 cells)
infectious disease with sepsis
(693 cells)
systemic lupus erythematosus
(405 cells)
post-COVID-19 disorder
(144 cells)
bacterial pneumonia
(120 cells)
influenza
(105 cells)
infectious disease
(80 cells)
viral pneumonia
(29 cells)
respiratory system disorder
(17 cells)
Cell Labels
Level_4
Description
Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method
manual
Cell Labels (7)
Cells (11,192)
HSC_MPP_CD38lo (HSC-like)
3,374
HSC_MPP_CMP
1,878
HSC_MPP_CMP_BEMP
1,612
HSC_MPP_CD38lo
1,523
HSC_MPP_CMP_ERYP
1,342
HSC_MPP_CLP
900
HSC_MPP_CMP_MEP
563
Level_1
Description
Similar clusters with shared features from level 2 were manually merged to one level higher in the hierarchy to determine clustering.
Annotation Method
manual
Cell Labels (1)
Cells (11,192)
HSPC
11,192
Level_2
Description
Similar clusters with shared features from level 3 were manually merged to one level higher in the hierarchy to determine clustering.
Annotation Method
manual
Cell Labels (1)
Cells (11,192)
HSPC
11,192
Level_3
Description
Similar clusters with shared features from level 4 were manually merged to one level higher in the hierarchy to determine clustering.
Annotation Method
manual
Cell Labels (2)
Cells (11,192)
HSC-like/prog
7,675
HSC Specialised
3,517
Molecular Data
