Human PBMC atlas - B memory cells

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Cell Metadata

B ISG switched memory

Full Name: IFN class switched memory B cell
Closest Ontology Term: class switched memory B cellCL:0000972
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: B cellCL:0000236
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster with canonical markers of class switched memory B cells in addition to interferon sensing genes
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: IGHG1, IGHG2, IGHG3, IGHG4, MX1, MX2, ISG15
Canonical Marker Genes: MS4A1, CD27
Rationale: Cluster with canonical markers of class switched memory B cells in addition to interferon sensing genes
Rationale DOI: https://doi.org/10.1016/j.immuni.2024.03.016

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual

Full Name: IFN class switched memory B cell
Closest Ontology Term: class switched memory B cellCL:0000972
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: B cellCL:0000236
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster with canonical markers of class switched memory B cells in addition to interferon sensing genes
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: IGHG1, IGHG2, IGHG3, IGHG4, MX1, MX2, ISG15
Canonical Marker Genes: MS4A1, CD27
Rationale: Cluster with canonical markers of class switched memory B cells in addition to interferon sensing genes
Rationale DOI: https://doi.org/10.1016/j.immuni.2024.03.016

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual