Human PBMC atlas - TCD4 naive cells

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Cell Metadata

T_unconventional

Full Name: unconventional central memory CD8-positive, alpha-beta T cell
Closest Ontology Term: central memory CD8-positive, alpha-beta T cellCL:0000907
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: CD8-positive, alpha-beta memory T cellCL:0000909
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: CD3+ T cell clusters that are either positive for both CD4 & CD8 or negative for both CD4 & CD8
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: unknown
Canonical Marker Genes: CD3D, CD3G, CD4, CD8A, CD8B
Rationale: CD3+ T cell clusters that are either positive for both CD4 & CD8 or negative for both CD4 & CD8
Rationale DOI: https://doi.org/10.3389/fimmu.2022.816005 https://doi.org/10.1016/j.autrev.2025.103757

Set of Labels Description: Similar clusters with shared features from level 3 were manually merged to one level higher in the hierarchy to determine clustering.
Annotation Method: manual

Full Name: unconventional central memory CD8-positive, alpha-beta T cell
Closest Ontology Term: central memory CD8-positive, alpha-beta T cellCL:0000907
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: CD8-positive, alpha-beta memory T cellCL:0000909
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: CD3+ T cell clusters that are either positive for both CD4 & CD8 or negative for both CD4 & CD8
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: unknown
Canonical Marker Genes: CD3D, CD3G, CD4, CD8A, CD8B
Rationale: CD3+ T cell clusters that are either positive for both CD4 & CD8 or negative for both CD4 & CD8
Rationale DOI: https://doi.org/10.3389/fimmu.2022.816005 https://doi.org/10.1016/j.autrev.2025.103757

Set of Labels Description: Similar clusters with shared features from level 3 were manually merged to one level higher in the hierarchy to determine clustering.
Annotation Method: manual