Human PBMC atlas - TCD4 naive cells

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Summary

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Cell Metadata

Summary

Our TCD4 naive cells dataset includes 1,631,434 cells, using canonical markers to distinguish 20 unique subsets.

Metadata

Dataset Type: Integrated. The file includes an integrated collection of datasets.
Total Cells: 1,625,425
organism: Homo sapiens
tissue: blood
assay: 10x 3' v2 (586,879 cells)10x 5' v1 (477,821 cells)10x 5' v2 (360,521 cells)10x 3' v3 (200,204 cells)
disease: normal (1,024,476 cells)COVID-19 (436,529 cells)systemic lupus erythematosus (94,906 cells)infectious disease with sepsis (31,433 cells)post-COVID-19 disorder (14,374 cells)respiratory system disorder (9,034 cells)bacterial pneumonia (7,722 cells)influenza (3,312 cells)infectious disease (3,042 cells)viral pneumonia (597 cells)

Cell Labels

Level_4

Description

Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.

Annotation Method

manual

T CD4 naive quiesc

499,018

T CD4 naive

210,325

T CD4 naive activ NR4A2

95,695

T CD4 CM KLRB1

88,201

T CD4 CM Th2 activ FOS_JUN LMNA

86,488

T CD4 CM Th2 activ FOS_JUN

81,079

T CD4 naive quiesc C1orf56

78,746

T CD4 naive CISH

72,946

T CD4 CM Th2

66,628

T CD4 naive activ FOS_JUN

59,581

T CD4 CM quiesc

52,778

T CD4 naive IFN

45,467

Level_1

Description

Similar clusters with shared features from level 2 were manually merged to one level higher in the hierarchy to determine clustering.

Annotation Method

manual

TCD4

1,617,613

TCD8_innate

7,812

Level_2

Description

Similar clusters with shared features from level 3 were manually merged to one level higher in the hierarchy to determine clustering.

Annotation Method

manual

T CD4 Naive

1,103,514

T CD4 Memory/Effector

514,099

T_unconventional

7,812

Level_3

Description

Similar clusters with shared features from level 4 were manually merged to one level higher in the hierarchy to determine clustering.

Annotation Method

manual

T CD4 Naive

1,103,514

T CD4 CM

490,067

T CD4 EM

24,032

7,812

Human PBMC atlas - TCD4 naive cells

Main

Cell Metadata

Summary

Our TCD4 naive cells dataset includes 1,631,434 cells, using canonical markers to distinguish 20 unique subsets.

Metadata

Dataset Type: Integrated. The file includes an integrated collection of datasets.
Total Cells: 1,625,425
organism: Homo sapiens
tissue: blood
assay: 10x 3' v2 (586,879 cells)10x 5' v1 (477,821 cells)10x 5' v2 (360,521 cells)10x 3' v3 (200,204 cells)
disease: normal (1,024,476 cells)COVID-19 (436,529 cells)systemic lupus erythematosus (94,906 cells)infectious disease with sepsis (31,433 cells)post-COVID-19 disorder (14,374 cells)respiratory system disorder (9,034 cells)bacterial pneumonia (7,722 cells)influenza (3,312 cells)infectious disease (3,042 cells)viral pneumonia (597 cells)