Human PBMC atlas - TCD4 effector and nonnaive cells

T CD4 CM Tfh activ FOS_JUN HLA

Full Name: HLA, FOS/JUN+ activated T Follicular Helper Cell
Closest Ontology Term: T follicular helper cellCL:0002038
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: central memory CD4-positive, alpha-beta T cellCL:0000904
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster with canonical markers of Tfh cells in addition to FOS/JUN markers of activation and HLA genes
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: FOS, JUN, HLA-DRB1, HLA-DRA
Canonical Marker Genes: CD4, MAF, PDCD1
Rationale: Cluster with canonical markers of Tfh cells in addition to FOS/JUN markers of activation and HLA genes
Rationale DOI: https://doi.org/10.1038/356801a0

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual