Human PBMC atlas - TCD4 effector and nonnaive cells

T CD4 EM Th1 activ NR4A2

Full Name: NR4A2+ activated T-helper 1 cell
Closest Ontology Term: T-helper 1 cellCL:0000545
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: effector memory CD4-positive, alpha-beta T cellCL:0000905
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster with canonical markers of Th1 cells in addition to NR4A2 marker of activation
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: NR4A2
Canonical Marker Genes: CD4, GZMA, GZMK, CXCR3
Rationale: Cluster with canonical markers of Th1 cells in addition to NR4A2 marker of activation
Rationale DOI: https://doi.org/10.1016/j.coi.2023.102285

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual