Human PBMC atlas - TCD4 effector and nonnaive cells

T CD4 EM Treg HLA DUSP4

Full Name: HLA, DUSP4+ effector memory regulatory T cell
Closest Ontology Term: regulatory T cellCL:0000815
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: regulatory T cellCL:0000815
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Regulatory T cells have been reported previously, but we differentiate subtypes, here defined by canonical effector memory genes and DUSP4+ in addition to HLA genes
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: DUSP4, HLA-DRB1, HLA-DRA
Canonical Marker Genes: CD4, FOXP3
Rationale: Regulatory T cells have been reported previously, but we differentiate subtypes, here defined by canonical effector memory genes and DUSP4+ in addition to HLA genes
Rationale DOI: https://doi.org/10.1002/eji.201041295

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual