Human Gut Cell Atlas (HGCA) v1 - Epithelial Lineage

Villus Tip Enterocytes

Ontology Term

enterocyteCL:0000584

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

enterocytes late, mature enterocyte

Category

Class of which the cell type is a subclass.

enterocyteCL:0000584

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

APOA1, APOC3, APOB, GUCA2A, CDHR5, DUOX2

Canonical Marker Genes

APOA1, APOC3, APOB

Rationale

Mature enterocytes at the tip of the villus, defined by absorptive machinery APOA1, APOC3, APOB, MTTP, CDHR5 and ACE2.

Inherited from hgca_celltype_v1

Set of Labels Description

Cell annotations based on two rounds of subclustering with scVI integration, sample_id as batch key. Cell annotations were refined by expert feedback based on "prelim annotation" on CAP. Prelim annotation is renamed "hgca_celltype_v0" here and the feedback on the "prelim annotation" is available by selecting a previous version of the Integrated Human Gut Atlas on CAP.

Annotation Method

both

Algorithm Name

scIB

Algorithm Version

1.2.1

Algorithm URL

https://github.com/theislab/scib