Human Gut Cell Atlas (HGCA) v1 - Myeloid Lineage

Cycling Macrophages

Ontology Term

cycling macrophageCL:4033076

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

proliferating macrophage, cycling macrophage

Category

Class of which the cell type is a subclass.

macrophageCL:0000235

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

STMN1, C1Q*

Canonical Marker Genes

STMN1, C1Q*

Negative Marker Genes

Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.

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Rationale

Macrophages that are dividing. They keep the macrophage identity through C1QB but bring up cell-cycle genes like STMN1, TUBB, MKI67 and PCNA.

Inherited from hgca_celltype_v1

Set of Labels Description

Cell annotations based on two rounds of subclustering with scVI integration, sample_id as batch key. Cell annotations were refined by expert feedback based on "prelim annotation" on CAP. Prelim annotation is renamed "hgca_celltype_v0" here and the feedback on the "prelim annotation" is available by selecting a previous version of the Integrated Human Gut Atlas on CAP.

Annotation Method

both

Algorithm Name

scIB

Algorithm Version

1.2.1

Algorithm URL

https://github.com/theislab/scib