Human Gut Cell Atlas (HGCA) v1 - Myeloid Lineage

M0 Macrophages

Ontology Term: M0 macrophageCL:0020017
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: tissue-resident macrophageCL:0000864
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: C1QA, C1QB, C1QC, CD163L1
Canonical Marker Genes: C1QA, C1QB, C1QC
Rationale: M0 macrophages are resident by C1Q, SELENOP, CD163L1, RNASEL1, presence in biopsies, but lack FOLR2, CD209, distinguishing them from other tissue resident macrophage subtypes
Rationale DOI: https://doi.org/10.1038/s41467-023-40156-6

Set of Labels Description: Cell annotations based on two rounds of subclustering with scVI integration, sample_id as batch key. Cell annotations were refined by expert feedback based on "prelim annotation" on CAP. Prelim annotation is renamed "hgca_celltype_v0" here and the feedback on the "prelim annotation" is available by selecting a previous version of the Integrated Human Gut Atlas on CAP.
Annotation Method: both
Algorithm Name: scIB
Algorithm Version: 1.2.1
Algorithm URL: https://github.com/theislab/scib