Human Gut Cell Atlas (HGCA) v1 - All Cells

CD8 IEL

Ontology Term: intraepithelial lymphocyteCL:0002496
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: IEL
Category Class of which the cell type is a subclass.: CD8-positive, alpha-beta T cellCL:0000625
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: ITGAE, CD160, KLRC2, KIR2DL4, NCR1, NCR2, NCR3, CD7, CD244
Canonical Marker Genes: ITGAE, CD69, CD160
Rationale: A large cluster of ITGAE high, CD160 exists in the atlas, pointing to resident status. contextualization with radial tissue terms could increase evidence

Set of Labels Description: Cell annotations based on two rounds of subclustering with scVI integration, sample_id as batch key. Cell annotations were refined by expert feedback based on "prelim annotation" on CAP. Prelim annotation is renamed "hgca_celltype_v0" here and the feedback on the "prelim annotation" is available by selecting a previous version of the Integrated Human Gut Atlas on CAP.
Annotation Method: both
Algorithm Name: scIB
Algorithm Version: 1.2.1
Algorithm URL: https://github.com/theislab/scib