The Human Neural Organoid Atlas

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Cell Metadata

Non-telencephalic NPC

Ontology Term: neural progenitor cellCL:0011020
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: non-terminally differentiated cellCL:0000055
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: No specific term available for non-telencephalic NPCs. Had to pick the generic npc term.
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: SOX2, OTX2, HOXB2, TFAP2A, CYP26A1
Canonical Marker Genes: SOX2, OTX2, HOXB2, TFAP2A, CYP26A1
Rationale: Cells expressing canonical non-telencephalic npc markers in organoids. Expression of SOX2 + any of the other genes is sufficient to classify a cell as of this type.

Set of Labels Description: Finer curated cell type annotation of the integrated HNOCA.
Annotation Method: both
Algorithm Name: snapseed
Algorithm Version: 0.1.0
Algorithm URL: https://github.com/devsystemslab/snapseed

Ontology Term: neural progenitor cellCL:0011020
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: non-terminally differentiated cellCL:0000055
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: No specific term available for non-telencephalic NPCs. Had to pick the generic npc term.
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: SOX2, OTX2, HOXB2, TFAP2A, CYP26A1
Canonical Marker Genes: SOX2, OTX2, HOXB2, TFAP2A, CYP26A1
Rationale: Cells expressing canonical non-telencephalic npc markers in organoids. Expression of SOX2 + any of the other genes is sufficient to classify a cell as of this type.

Set of Labels Description: Finer curated cell type annotation of the integrated HNOCA.
Annotation Method: both
Algorithm Name: snapseed
Algorithm Version: 0.1.0
Algorithm URL: https://github.com/devsystemslab/snapseed