Summary
This atlas is an integrated collection of over 182K cells, derived from single-cell RNA-seq data of the human retinal pigment epithelium and the choroid. These cells have been categorized into 15 major classes and 27 sub-classes.
Metadata
- Dataset Type
- Integrated. The file includes an integrated collection of datasets.
- Total Cells
- 182,151
- organism
- Homo sapiens
- tissue
- chorioretinal region (121,350 cells)optic choroid (52,307 cells)eyeball of camera-type eye (7,032 cells)pigmented layer of retina (1,462 cells)
- assay
- 10x 3' v3 (171,730 cells)10x 5' v2 (7,800 cells)10x 3' v2 (2,621 cells)
- disease
- normal
Cell Labels
Description
This cell annotation dataset focuses on the human retinal pigment epithelium (RPE) and choroid, which are essential for the survival and proper function of the neural retina in the human eye. Using single-cell RNA-seq (scRNA-seq), we analyzed over 180K cells from 67 donors. This comprehensive dataset enabled the identification 15 major cell classes and 27 sub-classes. As part of the Human Cell Atlas initiative, this resource lays a robust foundation for advancing research into the biology of the RPE and choroid and the diseases associated with these tissues.
Annotation Method
manual
