scRNA-seq of human of the human retinal pigment epithelium and the choroid

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Cell Metadata

NK_cells_GNLY

Ontology Term: natural killer cellCL:0000623
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: NK cell
Category Class of which the cell type is a subclass.: group 1 innate lymphoid cellCL:0001067
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: KLRD1, KLRF1, GNLY
Canonical Marker Genes: KLRD1
Rationale: This NK cell GNLY+ sub-class is annotated by the marker sKLRD1, KLRF1, GNLY

Set of Labels Description: This cell annotation dataset focuses on the human retinal pigment epithelium (RPE) and choroid, which are essential for the survival and proper function of the neural retina in the human eye. Using single-cell RNA-seq (scRNA-seq), we analyzed over 180K cells from 67 donors. This comprehensive dataset enabled the identification 15 major cell classes and 27 sub-classes. As part of the Human Cell Atlas initiative, this resource lays a robust foundation for advancing research into the biology of the RPE and choroid and the diseases associated with these tissues.
Annotation Method: manual

Ontology Term: natural killer cellCL:0000623
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: NK cell
Category Class of which the cell type is a subclass.: group 1 innate lymphoid cellCL:0001067
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: KLRD1, KLRF1, GNLY
Canonical Marker Genes: KLRD1
Rationale: This NK cell GNLY+ sub-class is annotated by the marker sKLRD1, KLRF1, GNLY

Set of Labels Description: This cell annotation dataset focuses on the human retinal pigment epithelium (RPE) and choroid, which are essential for the survival and proper function of the neural retina in the human eye. Using single-cell RNA-seq (scRNA-seq), we analyzed over 180K cells from 67 donors. This comprehensive dataset enabled the identification 15 major cell classes and 27 sub-classes. As part of the Human Cell Atlas initiative, this resource lays a robust foundation for advancing research into the biology of the RPE and choroid and the diseases associated with these tissues.
Annotation Method: manual