Cross-species Spinal Cord Atlas

Summary

Metadata

Dataset Type

Single. The file includes a single dataset whereby “dataset” means a single library or a set of technical replicates that can be combined without having to worry about the associated batch effect.

Total Cells

230,825

organism

Mus musculus (107,762 cells)Macaca mulatta (101,344 cells)Homo sapiens (21,719 cells)

tissue

Spinal cord

assay

10x multiome

disease

normal

anatomical_region

Cervical (63,312 cells)Thoracic (59,014 cells)Lumbar (55,563 cells)Sacral (50,755 cells)unknown (2,181 cells)

species

Mouse (107,762 cells)Macaque (101,344 cells)Human (21,719 cells)

nearest_development_origin

nan (79,631 cells)dl5 (18,648 cells)dl4 (17,259 cells)V1 (15,734 cells)dl1 (12,268 cells)dl2 (8,447 cells)FP (8,378 cells)dp2 (8,259 cells)dp3 (7,583 cells)dp6 (6,331 cells)Null_Neuron (5,044 cells)V0 (3,971 cells)RP (3,934 cells)dp1 (3,421 cells)Null_Progenitor (3,392 cells)V2b (3,081 cells)pMN (2,841 cells)MN (2,683 cells)V2a (2,670 cells)dl3 (2,351 cells)dp4 (2,337 cells)dl6 (2,286 cells)dp5 (2,051 cells)V3 (1,911 cells)p3 (1,825 cells)p1 (1,605 cells)p0 (1,080 cells)Outliers (1,052 cells)p2 (752 cells)

spinalcord_dissection

unknown (129,481 cells)Unbiased (61,319 cells)Ventral_horn (40,025 cells)

donor_name

Mouse_1 (107,762 cells)QN24.26.001 (40,592 cells)QN24.26.004 (27,053 cells)H20.30.002 (19,338 cells)QN23.26.012 (10,506 cells)QN23.26.001 (8,498 cells)QN22.26.011 (8,337 cells)QN22.26.016 (6,358 cells)H19.30.003 (1,203 cells)H19.30.001 (1,178 cells)

Cell Labels

Class

Description

Cell annotation set for Class

Annotation Method

manual

Cell Labels (6)

Cells (230,825)

Non-Neurons

122,011

Glutamatergic

56,875

GABAergic

47,969

Cholinergic

3,549

GABA-Gluta

344

???

77

Subclass

Description

Cell annotation set for Subclass

Annotation Method

manual

Cell Labels (22)

Cells (230,825)

Oligo

55,417

Gluta-D

34,322

Microglia

24,371

Astrocytes

22,423

GABA-D

22,101

GABA-V

18,483

Gluta-V

17,172

Ependymal

8,968

GABA-M

6,662

OPC

6,344

Gluta-M

5,381

Vascular

2,004

Group

Description

Cell annotation set for Group

Annotation Method

manual

Cell Labels (51)

Cells (230,825)

Oligo-1

28,359

Oligo-2

26,441

Microglia

24,371

Gluta-V-1

17,172

GABA-V-2

13,474

GM Astrocytes

11,844

WM Astrocytes

10,579

Ependymal

8,968

OPC

6,344

GABA-M-2

5,628

GABA-V-1

5,009

Gluta-Dorsal-10

4,751

Cluster

Description

Cell annotation set for Cluster

Annotation Method

manual

Cell Labels (258)

Cells (230,825)

2

19,424

17

18,170

105

16,136

231

10,261

25

8,570

132

7,322

106

5,645

145

5,202

104

4,024

9

3,865

124

3,861

7

3,858