Myeloid cells from human liver dataset

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Cell Metadata

ResKCs

Ontology Term: Kupffer cellCL:0000091
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: Resident Kupffer cells, KCs
Category Class of which the cell type is a subclass.: tissue-resident macrophageCL:0000864
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: TIMD4, SLC16A9, NDST3, KCNAB1, ITGAD, CD5L, VCAM1, SELENBP1, BCAM, CDH5
Canonical Marker Genes: CD5L, VSIG4, CD163, SLC40A1, TIMD4, SLC1A3, FOLR2, MARCO, GFRA2, ADRB1, TMEM26, HMOX1, SLC16A9, VCAM1, SUCNR1
Rationale: The marker genes are the top 10 DEGs between this population and the other myeloid cell types in the UMAP (from Table S2 in publication). In the publication we define a conserved mouse-human KC signature. These genes are listed as canonical marker genes for KCs.

Set of Labels Description: Annotation of cell types in dataset based on prior knowledge
Annotation Method: manual

Ontology Term: Kupffer cellCL:0000091
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: Resident Kupffer cells, KCs
Category Class of which the cell type is a subclass.: tissue-resident macrophageCL:0000864
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: TIMD4, SLC16A9, NDST3, KCNAB1, ITGAD, CD5L, VCAM1, SELENBP1, BCAM, CDH5
Canonical Marker Genes: CD5L, VSIG4, CD163, SLC40A1, TIMD4, SLC1A3, FOLR2, MARCO, GFRA2, ADRB1, TMEM26, HMOX1, SLC16A9, VCAM1, SUCNR1
Rationale: The marker genes are the top 10 DEGs between this population and the other myeloid cell types in the UMAP (from Table S2 in publication). In the publication we define a conserved mouse-human KC signature. These genes are listed as canonical marker genes for KCs.

Set of Labels Description: Annotation of cell types in dataset based on prior knowledge
Annotation Method: manual