HCA Gut Cell Atlas v1 Lymphoid Lineage

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Cell Metadata

CD8 Effector/Memory

Ontology Term: effector memory CD8-positive, alpha-beta T cell, terminally differentiatedCL:0001062
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: effector memory CD8 T cell, Teff/mem
Category Class of which the cell type is a subclass.: CD8-positive, alpha-beta T cellCL:0000625
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: IL2, GZMA, GZMK, GZMB, KLRG1
Canonical Marker Genes: GZMB, PRF1, KLRG1
Rationale: No CX3CR1 but IL2, granzymes, and CD8 signatures are found abundantly in single cell data of the gut

Set of Labels Description: Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering
Annotation Method: both
Algorithm Name: scVI
Algorithm Version: 1.3.2
Algorithm URL: https://github.com/scverse/scvi-tools

Ontology Term: effector memory CD8-positive, alpha-beta T cell, terminally differentiatedCL:0001062
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: effector memory CD8 T cell, Teff/mem
Category Class of which the cell type is a subclass.: CD8-positive, alpha-beta T cellCL:0000625
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: IL2, GZMA, GZMK, GZMB, KLRG1
Canonical Marker Genes: GZMB, PRF1, KLRG1
Rationale: No CX3CR1 but IL2, granzymes, and CD8 signatures are found abundantly in single cell data of the gut

Set of Labels Description: Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering
Annotation Method: both
Algorithm Name: scVI
Algorithm Version: 1.3.2
Algorithm URL: https://github.com/scverse/scvi-tools