HCA Gut Cell Atlas v1 Lymphoid Lineage

CD4 Treg

Ontology Term

regulatory T cellCL:0000815

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

Treg, regulatory CD4 T cell

Category

Class of which the cell type is a subclass.

CD4-positive, alpha-beta T cellCL:0000624

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

IL2RA, FOXP3, CTLA4, PDCD1, TIGIT, ICOS

Canonical Marker Genes

FOXP3, IL2RA, CTLA4

Rationale

Coexpress FOXP3 and IL2RA (CD25), FOXP3 expression quickly identifies clusters of T-regs

Inherited from Prelim annotation

Set of Labels Description

Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering

Annotation Method

both

Algorithm Name

scVI

Algorithm Version

1.3.2

Algorithm URL

https://github.com/scverse/scvi-tools