HCA Gut Cell Atlas v1 Lymphoid Lineage

ILC3

Ontology Term

group 3 innate lymphoid cell, humanCL:0001078

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

ILC3

Category

Class of which the cell type is a subclass.

innate lymphoid cellCL:0001065

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

KRT86, RORC, IL7R

Canonical Marker Genes

RORC, IL23R, IL22

Rationale

KRT86, RORC, IL7R and IL23R point to strong ILC3 signature, while some nearby subclusters show a more ILC or ILC2 tilt

Inherited from Prelim annotation

Set of Labels Description

Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering

Annotation Method

both

Algorithm Name

scVI

Algorithm Version

1.3.2

Algorithm URL

https://github.com/scverse/scvi-tools