HCA Gut Cell Atlas v1 Lymphoid Lineage

• v1 Integrated Human Gut Cell Atlas
• HCA Gut Cell Atlas v1 Lymphoid Lineage

CD8 Naive

Ontology Term

naive thymus-derived CD8-positive, alpha-beta T cellCL:0000900

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

naive CD8 T cell, Tnaive

Category

Class of which the cell type is a subclass.

CD8-positive, alpha-beta T cellCL:0000625

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

CD8A, LEF1, CCR7

Canonical Marker Genes

CCR7, LEF1, TCF7

Rationale

Proximity to other CD8 clusters and LEF1 expression allowed me to annotate this ~7k cell sub-cluster found amongst other CD4 clusters as CD8 naive.

Inherited from Prelim annotation

Set of Labels Description

Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering

Annotation Method

both

Algorithm Name

scVI

Algorithm Version

1.3.2

Algorithm URL

https://github.com/scverse/scvi-tools