This label represents superficial lamina propria fibroblasts that are ADAMDEC1+, ABCA8+, FABP4+ and form the dominant fibroblast population across datasets and samples. FOS+ Fibroblast Lamina propria or Ribo(high) Fibroblast Lamina propria, and note an upper-lamina WNT4+ subset (Stroma_0_2) described in the literature, as well as plasma (IGHA+) and myeloid (C1S/C1R+) doublet-contaminated clusters. Taken together, the transcriptional program, high dataset and sample diversity, and literature on WNT4+ villus-oriented fibroblasts support a high-confidence lamina propria fibroblast identity, with FOS and ribosomal signatures reflecting activation state rather than separate cell types.
Inherited from Prelim annotation
Set of Labels Description
Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering
