HCA Gut Cell Atlas v1 Epithelial Lineage

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Cell Metadata

Secretory Paneth Cells

Ontology Term: paneth cellCL:0000510
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: epithelial cellCL:0000066
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: DEFA5, DEFA6, LYZ, PRSS2, ITLN2, REG3A, PLA2G2A
Canonical Marker Genes: DEFA5, LYZ, PLA2G2A
Rationale: Paneth cells are found mostly in small intestine and are identified here with defensins DEFA* alongside high PLA2G2A. These are even rarer than tuft cells

Set of Labels Description: Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering
Annotation Method: algorithmic

Ontology Term: paneth cellCL:0000510
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: epithelial cellCL:0000066
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: DEFA5, DEFA6, LYZ, PRSS2, ITLN2, REG3A, PLA2G2A
Canonical Marker Genes: DEFA5, LYZ, PLA2G2A
Rationale: Paneth cells are found mostly in small intestine and are identified here with defensins DEFA* alongside high PLA2G2A. These are even rarer than tuft cells

Set of Labels Description: Cell annotations (Prelim annotation) are based on the finest possible label that could be used to describe each of the ~500 clusters found during integration and subclustering
Annotation Method: algorithmic