Cell Annotation Platform

v1 LNCS: Atlas of healthy human lymph nodes with and without ex vivo adjuvant stimulation
Human lymph nodes with partial T and B cell depletion

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An effort by the Villani, Gehlenborg, and Kharchenko labs.

Human lymph nodes with partial T and B cell depletion

Main

Cell Metadata

final annotation

DC

Ontology Term: dendritic cell, humanCL:0001056
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: dendritic cellCL:0000451
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: HLA-DRA, CD74, LAMP3, IDO1

Canonical Marker Genes

HLA-DRA, CD74, CLEC9A, CLEC10A,

Rationale

This cell type was annotated due to expression of many DC markers and antigen presentation molecules

Rationale DOI

10.1016/j.immuni.2024.01.006

Inherited from final annotation

Set of Labels Description: Cell annotations were based on the finest possible label that could describe the 16 clusters found following integration and clustering.
Annotation Method: manual