Integrated Human Breast Cell Atlas v1.0 - all cells

Basal-myoepithelial

Ontology Term

basal-myoepithelial cell of mammary glandCL:0002324

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

basal cell, myoepithelial cell, basal epithelial cell

Category

Class of which the cell type is a subclass.

epithelial cellCL:0000066

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

TAGLN, KRT14, ACTA2, TPM2, KRT17, MT2A

Canonical Marker Genes

KRT5, KRT14, TP63, ACTA2, MYLK, OXTR

Rationale

Basal-myoepithelial cells were identified and annotated based on canonical marker expression including KRT5, KRT14, TP63, and ACTA2. These cells represent the contractile, TP63+/KRT5+/KRT14+ basal layer that surrounds luminal epithelial cells in breast ducts and lobules.

Rationale DOI

10.1038/s41588-024-01688-910.1038/s41586-023-06252-9

Inherited from level1_annotation

Set of Labels Description

Cell annotations based on resolution broad clustering using the Leiden algorithm.

Annotation Method

manual