Integrated Human Breast Cell Atlas v1.0 - all cells

Perivascular

Ontology Term

perivascular cellCL:4033054

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

perivascular cell, mural cell, pericyte of breast

Category

Class of which the cell type is a subclass.

stromal cellCL:0000499

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

COL6A3, SERPINE1, CXCL3, CTSC, CFD, CD36

Canonical Marker Genes

RGS5, PDGFRB, ACTA2, MYH11, CALD1

Rationale

Perivascular cells (pericytes) were identified and annotated based on RGS5+/PDGFRB+/ACTA2+ expression. These mural cells surround blood vessel endothelium and regulate vascular tone. The label 'Perivascular' was used by original contributing studies; CL:4033054 is the matched ontology term.

Rationale DOI

10.1038/s41588-024-01688-910.1038/s41586-023-06252-9

Inherited from level1_annotation

Set of Labels Description

Cell annotations based on resolution broad clustering using the Leiden algorithm.

Annotation Method

manual