Integrated Human Breast Cell Atlas v1.0 - all cells

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Cell Metadata

Myeloid

Ontology Term: myeloid cellCL:0000763
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: myeloid leukocyte, myeloid immune cell
Category Class of which the cell type is a subclass.: leukocyteCL:0000738
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: The 'Myeloid' grouping is intentionally broad, consolidating macrophages, monocytes, dendritic cells, mast cells, and neutrophils under a single L1.0 label. CL:0000763 is used as the appropriate broad parent term.
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: APOE, GPNMB, IL1B, CCL3, TPSB2, FCER1A, CD1C, GZMB, S100A8
Canonical Marker Genes: LYZ, CD68, AIF1, CSF1R, CD14, FCGR3A
Rationale: The 'Myeloid' group was identified and annotated by Austin Reed, encompassing macrophages, monocytes, dendritic cells, mast cells, and neutrophils. Canonical markers LYZ, CD68, and AIF1 are shared across subtypes.
Rationale DOI: 10.1038/s41588-024-01688-9 10.1038/s41586-023-06252-9

Set of Labels Description: Cell annotations based on resolution broad clustering using the Leiden algorithm.
Annotation Method: manual

Ontology Term: myeloid cellCL:0000763
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: myeloid leukocyte, myeloid immune cell
Category Class of which the cell type is a subclass.: leukocyteCL:0000738
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: The 'Myeloid' grouping is intentionally broad, consolidating macrophages, monocytes, dendritic cells, mast cells, and neutrophils under a single L1.0 label. CL:0000763 is used as the appropriate broad parent term.
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: APOE, GPNMB, IL1B, CCL3, TPSB2, FCER1A, CD1C, GZMB, S100A8
Canonical Marker Genes: LYZ, CD68, AIF1, CSF1R, CD14, FCGR3A
Rationale: The 'Myeloid' group was identified and annotated by Austin Reed, encompassing macrophages, monocytes, dendritic cells, mast cells, and neutrophils. Canonical markers LYZ, CD68, and AIF1 are shared across subtypes.
Rationale DOI: 10.1038/s41588-024-01688-9 10.1038/s41586-023-06252-9

Set of Labels Description: Cell annotations based on resolution broad clustering using the Leiden algorithm.
Annotation Method: manual