Human intercostal skeletal muscle aging atlas (scRNA-seq and snRNA-seq, young vs aged)

VenEC

Ontology Term

vein endothelial cellCL:0002543

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

vein EC, post-capillary venule EC

Category

Class of which the cell type is a subclass.

endothelial cellCL:0000115

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

ACKR1, PLVAP, CCL14, ICAM1, SELE, RND1, RAMP3, CCL2

Canonical Marker Genes

ACKR1, NR2F2, EPHB4

Rationale

This cell was annotated manually using canonical markers in the field (ACKR1, PLVAP, CCL14) defining two subsets: VenEC and additional VenEC-CCL2+ which is high in CCL2, ICAM1, SELE, RND1. We noticed ACKR1, SELE, POSTN running differential expression. Venous endothelium.

Rationale DOI

10.1038/s41591-024-03376-x

Inherited from author_cell_type

Set of Labels Description

Displayed cell annotations represent 43 coarse cell type clusters derived using combined manual and automatic annotation using CellTypist.

Annotation Method

both

Algorithm Name

CellTypist

Algorithm Version

v1.7

Algorithm URL

https://github.com/Teichlab/celltypist