Human intercostal skeletal muscle aging atlas (scRNA-seq and snRNA-seq, young vs aged)

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Cell Metadata

VenEC

Ontology Term: vein endothelial cellCL:0002543
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: vein EC, post-capillary venule EC
Category Class of which the cell type is a subclass.: endothelial cellCL:0000115
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: ACKR1, PLVAP, CCL14, ICAM1, SELE, RND1, RAMP3, CCL2
Canonical Marker Genes: ACKR1, NR2F2, EPHB4
Rationale: This cell was annotated manually using canonical markers in the field (ACKR1, PLVAP, CCL14) defining two subsets: VenEC and additional VenEC-CCL2+ which is high in CCL2, ICAM1, SELE, RND1. We noticed ACKR1, SELE, POSTN running differential expression. Venous endothelium.
Rationale DOI: 10.1038/s41591-024-03376-x

Set of Labels Description: Displayed cell annotations represent 43 coarse cell type clusters derived using combined manual and automatic annotation using CellTypist.
Annotation Method: both
Algorithm Name: CellTypist
Algorithm Version: v1.7
Algorithm URL: https://github.com/Teichlab/celltypist

Ontology Term: vein endothelial cellCL:0002543
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: vein EC, post-capillary venule EC
Category Class of which the cell type is a subclass.: endothelial cellCL:0000115
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: ACKR1, PLVAP, CCL14, ICAM1, SELE, RND1, RAMP3, CCL2
Canonical Marker Genes: ACKR1, NR2F2, EPHB4
Rationale: This cell was annotated manually using canonical markers in the field (ACKR1, PLVAP, CCL14) defining two subsets: VenEC and additional VenEC-CCL2+ which is high in CCL2, ICAM1, SELE, RND1. We noticed ACKR1, SELE, POSTN running differential expression. Venous endothelium.
Rationale DOI: 10.1038/s41591-024-03376-x

Set of Labels Description: Displayed cell annotations represent 43 coarse cell type clusters derived using combined manual and automatic annotation using CellTypist.
Annotation Method: both
Algorithm Name: CellTypist
Algorithm Version: v1.7
Algorithm URL: https://github.com/Teichlab/celltypist