Human intercostal skeletal muscle aging atlas (scRNA-seq and snRNA-seq, young vs aged)

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Cell Metadata

CD4+T

Ontology Term: CD4-positive, alpha-beta T cellCL:0000624
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: CD4 T cell, T helper, CD4+ alpha-beta T lymphocyte
Category Class of which the cell type is a subclass.: alpha-beta T cellCL:0000789
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CD3D, IL7R, SELL, CCR7
Canonical Marker Genes: CD4, CD3D, IL7R
Rationale: This cell was annotated with CellTypist using the Immune_All_Low model trained on the cross-tissue immune cell atlas (DOI: 10.1126/science.abl5197). Canonical markers in the field include CD3D, IL7R, SELL, CCR7; we noticed IL7R, CD3D, CD3G running differential expression. Helper / regulatory T cell.
Rationale DOI: 10.1126/science.abl5197

Set of Labels Description: Displayed cell annotations represent 43 coarse cell type clusters derived using combined manual and automatic annotation using CellTypist.
Annotation Method: both
Algorithm Name: CellTypist
Algorithm Version: v1.7
Algorithm URL: https://github.com/Teichlab/celltypist

Ontology Term: CD4-positive, alpha-beta T cellCL:0000624
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: CD4 T cell, T helper, CD4+ alpha-beta T lymphocyte
Category Class of which the cell type is a subclass.: alpha-beta T cellCL:0000789
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CD3D, IL7R, SELL, CCR7
Canonical Marker Genes: CD4, CD3D, IL7R
Rationale: This cell was annotated with CellTypist using the Immune_All_Low model trained on the cross-tissue immune cell atlas (DOI: 10.1126/science.abl5197). Canonical markers in the field include CD3D, IL7R, SELL, CCR7; we noticed IL7R, CD3D, CD3G running differential expression. Helper / regulatory T cell.
Rationale DOI: 10.1126/science.abl5197

Set of Labels Description: Displayed cell annotations represent 43 coarse cell type clusters derived using combined manual and automatic annotation using CellTypist.
Annotation Method: both
Algorithm Name: CellTypist
Algorithm Version: v1.7
Algorithm URL: https://github.com/Teichlab/celltypist