Human intercostal skeletal muscle aging atlas (scRNA-seq and snRNA-seq, young vs aged)

MF-II

Ontology Term: fast muscle cellCL:0000190
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: fast-twitch myofiber, type II fiber, glycolytic myofiber, white fiber
Category Class of which the cell type is a subclass.: skeletal muscle fiberCL:0008002
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MYH2, MYH1, TNNT3, CKM
Canonical Marker Genes: MYH1, MYH2, TNNT3, MYL1
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: This cell was annotated manually using canonical fast-twitch myofiber markers in the field (MYH2, MYH1, TNNT3, CKM).
Rationale DOI: 10.1038/s41467-020-18789-8 10.1038/s41467-020-20064-9 10.1038/s41467-020-20063-w 10.1016/j.celrep.2017.05.054 10.1186/s13395-015-0046-6

Set of Labels Description: Displayed cell annotations represent 43 coarse cell type clusters derived using combined manual and automatic annotation using CellTypist.
Annotation Method: both
Algorithm Name: CellTypist
Algorithm Version: v1.7
Algorithm URL: https://github.com/Teichlab/celltypist