Single nucleus human kidney cell atlas

Main

Cell Metadata

Summary

The single nucleus integrated object of the HCKA contains ~200000 cells and 63 high resolution celltypes. This part of the HCKA contains healthy and disease states from diabetic kidney, polycystic kidney and acute kidney injury.

Metadata

Dataset Type: Integrated. The file includes an integrated collection of datasets.
Total Cells: 215,308
organism: Homo sapiens
tissue: kidney
assay: 10x 3' v3 (180,746 cells)10x 5' v2 (19,482 cells)10x 5' v1 (11,805 cells)10x 3' v1 (3,275 cells)
disease: normal (116,546 cells)polycystic kidney disease 1 (47,305 cells)acute kidney failure (37,952 cells)diabetic kidney disease (13,505 cells)

Cell Labels

coarse_annotation

Description

Cell annotations based on collapsing sn-fine-annotation to broader cell categories.

Annotation Method

manual

27,731

23,644

19,072

11,962

11,372

8,467

8,322

Interstitial_fibroblasts

8,226

aDCT

8,142

CD_ICA

6,986

Perivascular_fibroblasts

6,756

aCD_PC

6,287

fine_annotation

Description

Cell annotations based on resolution broad clustering using the Leiden algorithm.

Annotation Method

manual

16,575

14,054

11,372

11,292

11,156

9,590

8,965

8,322

8,142

7,780

6,986

6,287

Single nucleus human kidney cell atlas

Main

Cell Metadata

Summary

Metadata

Dataset Type: Integrated. The file includes an integrated collection of datasets.
Total Cells: 215,308
organism: Homo sapiens
tissue: kidney
assay: 10x 3' v3 (180,746 cells)10x 5' v2 (19,482 cells)10x 5' v1 (11,805 cells)10x 3' v1 (3,275 cells)
disease: normal (116,546 cells)polycystic kidney disease 1 (47,305 cells)acute kidney failure (37,952 cells)diabetic kidney disease (13,505 cells)