Publication
Single cell atlas of the human peripheral immune system
Our atlas represents a collaborative international effort to successfully integrate and annotate multiple large scale published and unpublished PBMC datasets spanning healthy and COVID patients. Using rigorous metrics for quality control we were formed a final integrated dataset of 8.4M cells. Consensus annotation was performed across multiple sites at high resolution, and ultimately defined 192 individual immune cell states in the peripheral blood.
Datasets (11)
- Human PBMC atlas - B memory cells337,659 cells
- Human PBMC atlas - plasma cells37,117 cells
- Human PBMC atlas - B naive cells463,552 cells
- Human PBMC atlas - T CD8 naive cells540,294 cells
- Human PBMC atlas - TCD4 effector and nonnaive cells749,849 cells
- Human PBMC atlas - TCD4 naive cells1,625,425 cells
- Human PBMC atlas - T CD8 effector and nonnaive cells and innate lymphoid cells including NK cells2,216,128 cells
- Human PBMC atlas - T/NK proliferating cells102,483 cells
- Human PBMC atlas - DC_DC2 cells145,941 cells
- Human PBMC atlas - HSCs11,192 cells
- Human PBMC atlas - MonoDC2 cells2,276,385 cells
