• v2 An integrated cell atlas of the human liver in health and disease
• Human liver cell atlas - all cells

Summary

Metadata

Dataset Type

Integrated. The file includes an integrated collection of datasets.

Total Cells

524,699

assay

10x 3' v3 (324,241 cells)10x 3' v2 (157,663 cells)10x 5' v1 (42,795 cells)

disease

normal

organism

Homo sapiens

tissue

liver (233,979 cells)caudate lobe of liver (198,527 cells)left lobe of liver (53,491 cells)right lobe of liver (38,702 cells)

Cell Labels

author_cell_type

Description

HLiCA classifies cells into six lineages and 47 distinct cell types. Rigorous benchmarking ensured robust integration across technical and biological variables. Expanded annotations allowed identification of previously undetected liver cell types. As the largest human liver cell atlas, HLiCA serves as a genetically diverse, well-annotated reference.

Annotation Method

algorithmic

Cell Labels (48)

Cells (524,699)

Periportal Hepatocyte

86,306

Ribosomal+ Hepatocyte

76,787

Pericentral Hepatocyte

37,364

CD8 T Cell

30,340

Periportal LSEC

28,433

Classical Monocytes

23,980

Hepatic Artery

23,642

Central Venous LSEC

22,202

Vascular Smooth Muscle Cell

15,849

Dim NK Cell

13,543

MAIT T Cell

13,497

Bright NK Cell

12,851