Macrophages

Ontology Term

macrophageCL:0000235

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

unknown

Category

Class of which the cell type is a subclass.

mononuclear phagocyteCL:0000113

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

NDST3, CD5L, LILRB5, SDC3, FOLR2, C1QC, C1QB, CTD-2337J16.1, SIGLEC1, C1QA

Canonical Marker Genes

CSF1R, MAFB

Rationale

Marker genes are top 10 DEGs for this population compared with rest of UMAP (from Table S1 in publication). As most of the population are Kupffer cells (KCs), KC specific genes largely define the population however smaller populations of macrophages are also present. Refer to myeloid cell UMAP for more granularity.

Inherited from author_cell_type

Set of Labels Description

Annotation of cells in dataset based on prior knowledge.

Annotation Method

manual