Summary
The main parenchymal liver cells responsible for metabolism, detoxification, and protein synthesis.
These are version 1 cell type labels and may be subject to change.
Metadata
- Dataset Type
- Integrated. The file includes an integrated collection of datasets.
- Total Cells
- 228,368
- organism
- Homo sapiens
- tissue
- caudate lobe of liver (141,620 cells)liver (86,607 cells)left lobe of liver (108 cells)right lobe of liver (33 cells)
- assay
- 10x 3' v3 (118,100 cells)10x 3' v2 (74,599 cells)10x 5' v1 (35,669 cells)
- disease
- normal
Cell Labels
Description
HLiCA classifies cells into six lineages and 48 distinct cell types, 18 more than previous studies. Rigorous benchmarking ensured robust integration across technical and biological variables. Expanded annotations allowed identification of previously undetected liver cell types. As the largest human liver cell atlas, HLiCA serves as a genetically diverse, well-annotated reference.
Annotation Method
both
