Single-nucleus transcriptomic profiling of human skeletal muscle from healthy adults

Vascular Endothelial Cell

Ontology Term: blood vessel endothelial cellCL:0000071
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: endothelial cell of vascular treeCL:0002139
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: VWF, PECAM1, KDR, CDH5, SPARCL1, CD36, PTPRM
Canonical Marker Genes: ADGRF5, B2M, PTPRB, TIMP3, PECAM1, VWF
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: Endothelial cells were defined by high expression of vascular markers VWF, CD36, SPARCL1, LDB2, PTPRM, TIMP3, and DOCK9, with VWF and SPARCL1 being among the most specific differentially expressed genes.

Set of Labels Description: Cell annotations were generated with scType using marker genes curated from related publications, and then manually reviewed and adjusted based on the top highly variable genes in each Leiden cluster.
Annotation Method: both
Algorithm Name: scType
Algorithm Version: v1
Algorithm URL: https://github.com/IanevskiAleksandr/sc-type