Single-nucleus transcriptomic profiling of human skeletal muscle from healthy adults

Muscle Satellite Cell

Ontology Term: skeletal muscle satellite cellCL:0000594
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: cell of skeletal muscleCL:0000188
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MUSK, LAMA2, CADM2, TLN2, PTPRG, RBMS3
Canonical Marker Genes: CADM2, LAMA2, MEG3, MEG8, NCAM1, PAX7
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: This cluster was annotated as muscle satellite cells given enrichment of neuromuscular and progenitor-associated genes including MUSK, LAMA2, CADM2, TLN2, PTPRG, and RBMS3.

Set of Labels Description: Cell annotations were generated with scType using marker genes curated from related publications, and then manually reviewed and adjusted based on the top highly variable genes in each Leiden cluster.
Annotation Method: both
Algorithm Name: scType
Algorithm Version: v1
Algorithm URL: https://github.com/IanevskiAleksandr/sc-type