Single-nucleus transcriptomic profiling of human skeletal muscle from healthy adults

Muscle Satellite Cell

Ontology Term

skeletal muscle satellite cellCL:0000594

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

unknown

Category

Class of which the cell type is a subclass.

cell of skeletal muscleCL:0000188

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

—

Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

MUSK, LAMA2, CADM2, TLN2, PTPRG, RBMS3

Canonical Marker Genes

CADM2, LAMA2, MEG3, MEG8, NCAM1, PAX7

Rationale

This cluster was annotated as muscle satellite cells given enrichment of neuromuscular and progenitor-associated genes including MUSK, LAMA2, CADM2, TLN2, PTPRG, and RBMS3.

Inherited from author_cell_type

Set of Labels Description

Cell annotations were generated with scType using marker genes curated from related publications, and then manually reviewed and adjusted based on the top highly variable genes in each Leiden cluster.

Annotation Method

both

Algorithm Name

scType

Algorithm Version

v1

Algorithm URL

https://github.com/IanevskiAleksandr/sc-type

• v1 Tissue-wide single-cell multiomic analysis of human gene regulation and cell diversity
• Single-nucleus transcriptomic profiling of human skeletal muscle from healthy adults