Single-nucleus transcriptomic profiling of human skeletal muscle from healthy adults

Mast Cell

Ontology Term

mast cellCL:0000097

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

unknown

Category

Class of which the cell type is a subclass.

myeloid leukocyteCL:0000766

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

KIT, FCER1A, FCER1G, CPA3, TPSAB1/TPSB2, SLC24A3, IL18R1

Canonical Marker Genes

CD69, CPA3, KIT, TPSAB1, TPSB2

Rationale

Cells in this cluster exhibit a mast cell phenotype, marked by KIT, SLC24A3, IL18R1, SYTL3, and CHN2, with particularly high and selective expression of KIT and SLC24A3.

Inherited from author_cell_type

Set of Labels Description

Cell annotations were generated with scType using marker genes curated from related publications, and then manually reviewed and adjusted based on the top highly variable genes in each Leiden cluster.

Annotation Method

both

Algorithm Name

scType

Algorithm Version

v1

Algorithm URL

https://github.com/IanevskiAleksandr/sc-type