Lazarescu 2025 — abdominal visceral adipose tissue

Main

Cell Metadata

Summary

Single nucleus RNA sequencing profiles of five paired samples of human subcutaneous and visceral (omental) adipose tissue, and five additional samples of visceral adipose tissue. All were taken from relatively healthy humans, with normal-weight to obese range BMI (without obesity complications)

Metadata

Dataset Type: Integrated. The file includes an integrated collection of datasets.
Total Cells: 83,731
organism: Homo sapiens
tissue: visceral abdominal adipose tissue
assay: 10x 3' v3
disease: morbid obesity (32,563 cells)normal (20,859 cells)type 2 diabetes mellitus (18,597 cells)obesity disorder (11,712 cells)

Cell Labels

author_cell_type

Description

Cell subsets were annotated using known markers from the literature (such as ADIPOQ and AQP7 for adipocytes), expert knowledge and CellTypist R package v.2. Detailed description of the annotation of nonadipocytes appears in PMID 39071890.

Annotation Method

both

mesothelial cell

30,080

mesenchymal stem cell of adipose tissue

15,509

adipocyte of omentum tissue

15,460

macrophage

6,666

endothelial cell

4,893

T cell

2,817

myeloid lineage restricted progenitor cell

2,280

mural cell

2,063

endothelial cell of lymphatic vessel

1,706

monocyte

932

unknown

502

mast cell

459

Lazarescu 2025 — abdominal visceral adipose tissue

Main

Summary

Feedback

Cell Metadata

author_cell_type

Summary

Metadata

Dataset Type: Integrated. The file includes an integrated collection of datasets.
Total Cells: 83,731
organism: Homo sapiens
tissue: visceral abdominal adipose tissue
assay: 10x 3' v3
disease: morbid obesity (32,563 cells)normal (20,859 cells)type 2 diabetes mellitus (18,597 cells)obesity disorder (11,712 cells)