Gene Filtering
CAP automatically filters out genes which are often over-expressed but biologically non-informative. The following genes are filtered out when reporting differentially expressed genes displayed on the heatmap:
- Mitochondrial genes and pseudogenes
- Ribosomal genes and pseudogenes
- Long non-coding RNA
- TCR genes with exceptions for: TRAV1-2, TRGV9, TRDV2
- BCR genes
For more detailed information see the GitHub repo here: cap-gene-filtering