This atlas is an integrated collection of over 1M cells, derived from single-nucleus RNA-seq data of the human trabecular meshwork and ciliary body. These cells have been categorized into 9 major classes and 18 sub-classes.
Metadata
Dataset Type
Integrated. The file includes an integrated collection of datasets.
This cell annotation set focuses on the trabecular meshwork (TM) and ciliary body (CB), key tissues regulating aqueous humor dynamics and intraocular pressure in the human eye. Using single-nucleus RNA-seq, we analyzed over 1 million cells from 70 healthy donors, identifying 9 major cell classes and 18 sub-classes. As part of the Human Cell Atlas initiative, this dataset integrates transcriptomic and chromatin accessibility data and is publicly accessible via CELLxGENE and the UCSC Cell Browser, offering a valuable resource for understanding ocular physiology and disease mechanisms.
